Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-(2-(4-(5-methyl-1-(4-oxo-3,4-dihydropyrrolo[1,2-f][1,2,4]triazin-2-yl)-1H-pyrazole-4-carbonyl)piperazin-1-yl)thiazol-5-yl)benzonitrile
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 PubChem ID
CID: 137049599
Canonical SMILES
Cc1c(C(=O)N2CCN(c3ncc(-c4ccc(C#N)cc4)s3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1
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Compound Formula C25H21N9O2S
Compound Structure
Protein Name
 Protein Info 
Sepiapterin reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P35270
Gene Name
SPR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 160 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 10 nM