Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(4-(6,6-difluoro-2-azaspiro[3.3]heptane-2-carbonyl)-5-methyl-1H-pyrazol-1-yl)-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one
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 PubChem ID
CID: 137128271
Canonical SMILES
Cc1c(C(=O)N2CC3(C2)CC(F)(F)C3)cnn1-c1nc2[nH]ccc2c(=O)[nH]1
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Compound Formula C17H16F2N6O2
Compound Structure
Protein Name
 Protein Info 
Sepiapterin reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P35270
Gene Name
SPR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 370 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 100 nM