Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(1-isopropyl-4-(3,3,3-trifluoroprop-1-en-2-yl)-1H-pyrazol-5-yl)-5-methyl-1-(4-oxo-3,4-dihydropyrrolo[1,2-f][1,2,4]triazin-2-yl)-1H-pyrazole-4-carboxamide
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 PubChem ID
CID: 137049680
Canonical SMILES
C=C(c1cnn(C(C)C)c1NC(=O)c1cnn(-c2nn3cccc3c(=O)[nH]2)c1C)C(F)(F)F
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Compound Formula C20H19F3N8O2
Compound Structure
Protein Name
 Protein Info 
Sepiapterin reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P35270
Gene Name
SPR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 310 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3 nM