Brief Information of the Compound and Protein
Compound Name
N-(3-carbamoyl-1-methyl- 1H-pyrazol-4-yl)-5- piperazin-1- ylpyrazolo[1,5- a]pyrimidine-3- carboxamide hydrochloride
    Show/Hide
PubChem ID
CID: 121493987
Canonical SMILES
Cn1cc(NC(=O)c2cnn3ccc(nc23)N2CCNCC2)c(n1)C(N)=O
    Show/Hide
Compound Formula C16H19N9O2
Compound Structure
Protein Name
Interleukin-1 receptor-associated kinase 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase IRAK family
Uniprot ID
Q9NWZ3
Gene Name
IRAK4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 38 nM
   TI
   LI
   LO
   TS
CL000864 THP1-Xblue Homo sapiens (Human)  1
1
IC50 = 150 nM
   TI
   LI
   LO
   TS