Brief Information of the Compound and Protein
Compound Name
N-(3-carbamoyl-1-methylpyrazol-4-yl)-6-(1-methylpyrazol-4-yl)pyridine-2-carboxamide
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PubChem ID
CID: 73442848
Canonical SMILES
Cn1cc(cn1)-c1cccc(n1)C(=O)Nc1cn(C)nc1C(N)=O
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Compound Formula C15H15N7O2
Compound Structure
Protein Name
Interleukin-1 receptor-associated kinase 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase IRAK family
Uniprot ID
Q9NWZ3
Gene Name
IRAK4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 36 nM
   TI
   LI
   LO
   TS
CL000864 THP1-Xblue Homo sapiens (Human)  1
1
IC50 = 138 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 32 nM