Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-[(2R,5R)-2-methyl-5-phenylmorpholin-4-yl]-4H-pyrido[3,2-b][1,4]oxazin-3-one
    Show/Hide
 PubChem ID
CID: 54592009
SID: 131341817
Canonical SMILES
C[C@@H]1CN([C@@H](CO1)c1ccccc1)c1ccc2OCC(=O)Nc2n1
    Show/Hide
Compound Formula C18H19N3O3
Compound Structure
Protein Name
 Protein Info 
Mineralocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 2
Uniprot ID
P08235
Gene Name
NR3C2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000148 Huh-7
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 33 nM
   TI
   LI
   LO
   TS
2
IC50 = 44 nM
   TI
   LI
   LO
   TS
3
IC50 = 44.4 nM
   TI
   LI
   LO
   TS
CL000952 UAS-MR-bla HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 199.53 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 25 nM
2 Ki = 6.3 nM
3 Ki = 25.12 nM