Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2R)-2-(5-fluoro-2-hydroxyphenyl)-2-(3-oxo-1H-isoindol-2-yl)-N-(1,3-thiazol-2-yl)acetamide
    Show/Hide
 PubChem ID
CID: 125461985
Canonical SMILES
Oc1ccc(F)cc1[C@@H](N1Cc2ccccc2C1=O)C(=O)Nc1nccs1
    Show/Hide
Compound Formula C19H14FN3O3S
Compound Structure
Protein Name
 Protein Info 
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3
 Cell Line Info 
Mus musculus (Mouse)  4
1
IC50 = 250 nM
   TI
   LI
   LO
   TS
2
IC50 = 470 nM
   TI
   LI
   LO
   TS
3
IC50 = 840 nM
   TI
   LI
   LO
   TS
4
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  4
1
IC50 = 2 nM
   TI
   LI
   LO
   TS
2
IC50 = 4.7 nM
   TI
   LI
   LO
   TS
3
IC50 = 8.8 nM
   TI
   LI
   LO
   TS
4
IC50 > 1000 nM
   TI
   LI
   LO
   TS