Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4'-[1-(5-fluoro-6-trifluoromethyl-1H-benzoimidazol-2-yl)-6-(pyrrolidine-1-carbonyl)-6-aza-spiro[2.5]oct-1-yl]-biphenyl-3-carbonitrile
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 PubChem ID
CID: 11527169
SID: 16629075
Canonical SMILES
Fc1cc2[nH]c(nc2cc1C(F)(F)F)C1(CC11CCN(CC1)C(=O)N1CCCC1)c1ccc(cc1)-c1cccc(c1)C#N
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Compound Formula C33H29F4N5O
Compound Structure
Protein Name
 Protein Info 
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 44 nM
   TI
   LI
   LO
   TS