Brief Information of the Compound and Protein
Compound Name
N-[5-[6-[[2-methoxy-6-(4-methylpiperazin-1-yl)pyridin-3-yl]amino]-3-piperidin-1-ylpyridin-2-yl]oxy-2-methylphenyl]prop-2-enamide
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PubChem ID
CID: 148967294
Canonical SMILES
COc1nc(ccc1Nc1ccc(N2CCCCC2)c(Oc2ccc(C)c(NC(=O)C=C)c2)n1)N1CCN(C)CC1
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Compound Formula C31H39N7O3
Compound Structure
Protein Name
Dipeptidyl peptidase 1
Protein Classification
Enzyme
>
Protease
>
Cysteine protease
>
Cysteine protease CA clan
>
Cysteine protease C1A family
Uniprot ID
P53634
Gene Name
CTSC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 6.5 nM
   TI
   LI
   LO
   TS
CL000100 U-937 Homo sapiens (Human)  1
1
IC50 = 10 nM
   TI
   LI
   LO
   TS