Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[2-methoxy-5-[6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-pyrrolidin-1-ylpyridin-2-yl]oxyphenyl]prop-2-enamide
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 PubChem ID
CID: 152242423
Canonical SMILES
COc1ccc(Oc2nc(Nc3ccc(cc3OC)N3CCN(C)CC3)ccc2N2CCCC2)cc1NC(=O)C=C
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Compound Formula C31H38N6O4
Compound Structure
Protein Name
 Protein Info 
Dipeptidyl peptidase 1
Protein Classification
Enzyme
>
Protease
>
Cysteine protease
>
Cysteine protease CA clan
>
Cysteine protease C1A family
Uniprot ID
P53634
Gene Name
CTSC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 21.3 nM
   TI
   LI
   LO
   TS
CL000100 U-937
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 70 nM
   TI
   LI
   LO
   TS