Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[2-methyl-5-[6-[4-(4-methylpiperazin-1-yl)anilino]-3-piperidin-1-ylpyridin-2-yl]oxyphenyl]prop-2-enamide
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 PubChem ID
CID: 148412521
Canonical SMILES
CN1CCN(CC1)c1ccc(Nc2ccc(N3CCCCC3)c(Oc3ccc(C)c(NC(=O)C=C)c3)n2)cc1
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Compound Formula C31H38N6O2
Compound Structure
Protein Name
 Protein Info 
Dipeptidyl peptidase 1
Protein Classification
Enzyme
>
Protease
>
Cysteine protease
>
Cysteine protease CA clan
>
Cysteine protease C1A family
Uniprot ID
P53634
Gene Name
CTSC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 2.7 nM
   TI
   LI
   LO
   TS
CL000100 U-937
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 5.8 nM
   TI
   LI
   LO
   TS