Brief Information of the Compound and Protein
Compound Name
2-[4-(5-chloropyridin-2-yl)piperazin-1-yl]-N-(3-ethylphenyl)acetamide
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PubChem ID
CID: 155516494
Canonical SMILES
CCc1cccc(NC(=O)CN2CCN(CC2)c2ccc(Cl)cn2)c1
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Compound Formula C19H23ClN4O
Compound Structure
Protein Name
D(4) dopamine receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P21917
Gene Name
DRD4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
IC50 = 7059 nM
   TI
   LI
   LO
   TS
2
IC50 = 10449 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 172.2 nM
   TI
   LI
   LO
   TS