Bioactivity Information | MolBiC

Brief Information of the Compound and Protein

Compound Name

Compound Info

VELPATASVIR

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PubChem ID

CID: 67683363

Canonical SMILES	COC[C@H]1C[C@@H](c2nc(-c3ccc4c(c3)COc3cc5c(ccc6nc([C@@H]7CC[C@H](C)N7C(=O)[C@@H](NC(=O)OC)C(C)C)[nH]c65)cc3-4)c[nH]2)N(C(=O)[C@H](NC(=O)OC)c2ccccc2)C1 Show/Hide
Compound Formula	C49H54N8O8

Compound Structure

Protein Name

Protein Info

Nonstructural protein 5A

Protein Classification

Unclassified protein

Uniprot ID

Q5L478

Gene Name

NS5A

Table of Molecular Bioactivities Related to the Compound and Protein

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000148	Huh-7 Cell Line Info	Homo sapiens (Human)	16
1	EC50 = 0.01 nM	TI LI LO TS
2	EC50 = 0.011 nM	TI LI LO TS
3	EC50 = 0.013 nM	TI LI LO TS
4	EC50 = 0.014 nM	TI LI LO TS
5	EC50 = 0.016 nM	TI LI LO TS
6	EC50 = 0.031 nM	TI LI LO TS
7	EC50 = 0.032 nM	TI LI LO TS
8	EC50 = 0.053 nM	TI LI LO TS
9	EC50 = 0.054 nM	TI LI LO TS
10	EC50 = 0.105 nM	TI LI LO TS
11	EC50 = 0.13 nM	TI LI LO TS
12	EC50 = 0.21 nM	TI LI LO TS
13	EC50 = 0.22 nM	TI LI LO TS
14	EC50 = 0.25 nM	TI LI LO TS
15	EC50 = 3.2 nM	TI LI LO TS
16	EC50 = 8.5 nM	TI LI LO TS