Brief Information of the Compound and Protein
Compound Name
 Compound Info 
7-[(R)-2-((E)-(S)-3-Hydroxy-oct-1-enyl)-5-oxo-pyrrolidin-1-yl]-heptanoic acid
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 PubChem ID
CID: 44289922
Canonical SMILES
CCCCC[C@H](O)\C=C\[C@H]1CCC(=O)N1CCCCCCC(O)=O
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Compound Formula C19H33NO4
Compound Structure
Protein Name
 Protein Info 
Prostaglandin E2 receptor EP4 subtype
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Prostanoid receptor
Uniprot ID
P35408
Gene Name
PTGER4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 56 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 1.606 nM
   TI
   LI
   LO
   TS
CL000314 HEK293T/17
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 0.065 nM
   TI
   LI
   LO
   TS
2
EC50 = 1.765 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 4.5 nM