Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[(1S)-1-[[5-[(E)-prop-1-enyl]-3-[[4-(trifluoromethyl)phenyl]methyl]triazole-4-carbonyl]amino]ethyl]benzoic acid
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 PubChem ID
CID: 146014480
Canonical SMILES
C\C=C\c1nnn(Cc2ccc(cc2)C(F)(F)F)c1C(=O)N[C@@H](C)c1ccc(cc1)C(O)=O
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Compound Formula C23H21F3N4O3
Compound Structure
Protein Name
 Protein Info 
Prostaglandin E2 receptor EP4 subtype
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
Prostanoid receptor
Uniprot ID
P35408
Gene Name
PTGER4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 6.1 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  4
1
IC50 = 0.4 nM
   TI
   LI
   LO
   TS
2
IC50 = 5.2 nM
   TI
   LI
   LO
   TS
3
IC50 = 18.7 nM
   TI
   LI
   LO
   TS
4
Kd = 5.623 nM
   TI
   LI
   LO
   TS