Brief Information of the Compound and Protein
Compound Name
 Compound Info 
CHEBI:46024
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 PubChem ID
CID: 444732
SID: 12013760
Canonical SMILES
C[C@H](\C=C(/C)\C=C\C(=O)NO)C(=O)c1ccc(cc1)N(C)C
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Compound Formula C17H22N2O3
Compound Structure
Protein Name
 Protein Info 
Histone deacetylase 2
Protein Classification
Epigenetic regulator
>
Eraser
>
Histone deacetylase
>
HDAC class I
Uniprot ID
Q92769
Gene Name
HDAC2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 25 nM
   TI
   LI
   LO
   TS
2
IC50 = 39.5 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 2.74 nM
   TI
   LI
   LO
   TS
2
IC50 = 5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1 nM
2 IC50 = 1.1 nM
3 IC50 = 4 nM
4 IC50 = 6.08 nM
5 IC50 = 10 nM
6 IC50 = 14 nM
7 IC50 = 14.8 nM
8 IC50 = 15 nM
9 IC50 = 18 nM
10 IC50 = 20.5 nM
11 IC50 = 22.95 nM
12 IC50 = 23 nM
13 IC50 = 23.6 nM
14 IC50 = 24 nM
15 IC50 = 25 nM
16 IC50 = 28.2 nM
17 IC50 = 32.1 nM
18 IC50 = 39 nM
19 IC50 = 39.1 nM
20 IC50 = 46.6 nM
21 IC50 = 52 nM
22 IC50 = 68 nM
23 IC50 = 96 nM
24 IC50 = 7600 nM
25 Ki = 0.65 nM
26 Ki = 0.7 nM
27 Ki = 0.76 nM
28 Ki = 1.06 nM