Brief Information of the Compound and Protein
| Compound Name |
5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]pyrimidine-2,4-diamine
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PubChem ID | |||||
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Compound Structure |
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| Protein Name |
Macrophage colony-stimulating factor 1 receptor
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Protein Classification |
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase PDGFR family
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| Uniprot ID | Gene Name | CSF1R |
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Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Biochemical Assays
| 1 | IC50 = 30 nM | ||
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| 2 | IC50 = 60 nM | ||
| 3 | IC50 = 470 nM | ||
| 4 | Kd = 1.6 nM | ||
| 5 | Kd = 2.2 nM | ||