Brief Information of the Compound and Protein
Compound Name
3,4-dimethyl-N-[1-[6-(trifluoromethyl)pyridin-2-yl]azetidin-3-yl]cinnoline-6-carboxamide
    Show/Hide
PubChem ID
CID: 135126261
Canonical SMILES
Cc1nnc2ccc(cc2c1C)C(=O)NC1CN(C1)c1cccc(n1)C(F)(F)F
    Show/Hide
Compound Formula C20H18F3N5O
Compound Structure
Protein Name
Metabotropic glutamate receptor 4
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
Q14833
Gene Name
GRM4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 3363 nM
   TI
   LI
   LO
   TS