Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-4-(1-(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethylamino)-2-methoxybenzonitrile
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 PubChem ID
CID: 118955607
Canonical SMILES
COc1cc(N[C@@H](C)c2cc3cc(Cl)ccc3[nH]c2=O)ccc1C#N
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Compound Formula C19H16ClN3O2
Compound Structure
Protein Name
 Protein Info 
Isocitrate dehydrogenase [NADP] cytoplasmic
Protein Classification
Enzyme
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Oxidoreductase
Uniprot ID
O75874
Gene Name
IDH1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000067 HCT 116
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 7 nM
   TI
   LI
   LO
   TS
2
IC50 = 213 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 < 10 nM
2 IC50 = 14 nM
3 IC50 = 111 nM