Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-5-((1-(6-Chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl)amino)-6-methoxypicolinonitrile
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 PubChem ID
CID: 118956187
Canonical SMILES
COc1nc(C#N)ccc1N[C@@H](C)c1cc2cc(Cl)ccc2[nH]c1=O
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Compound Formula C18H15ClN4O2
Compound Structure
Protein Name
 Protein Info 
Isocitrate dehydrogenase [NADP] cytoplasmic
Protein Classification
Enzyme
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Oxidoreductase
Uniprot ID
O75874
Gene Name
IDH1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000067 HCT 116
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 185.1 nM
   TI
   LI
   LO
   TS
2
IC50 = 338 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 44 nM
2 IC50 = 1015 nM