Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-fluoro-3-phenyl-2-[(1S)-1-(7H-purin-6-ylamino)propyl]quinazolin-4-one
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 PubChem ID
CID: 11625818
SID: 16728852
Canonical SMILES
CC[C@H](Nc1ncnc2nc[nH]c12)c1nc2cccc(F)c2c(=O)n1-c1ccccc1
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Compound Formula C22H18FN7O
Compound Structure
Protein Name
 Protein Info 
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
O00329
Gene Name
PIK3CD
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 8 nM
2 IC50 = 1.2 nM
3 IC50 = 1.6 nM
4 IC50 = 2 nM
5 IC50 = 2.1 nM
6 IC50 = 2.5 nM
7 IC50 = 2.7 nM
8 IC50 = 3 nM
9 IC50 = 3.1 nM
10 IC50 = 3.2 nM
11 IC50 = 4.3 nM
12 IC50 = 4.7 nM
13 IC50 = 5.9 nM
14 IC50 = 6 nM
15 IC50 = 7 nM
16 IC50 = 9 nM
17 IC50 = 10 nM
18 IC50 = 19 nM
19 IC50 = 24 nM
20 IC50 = 25 nM
21 IC50 = 31 nM
22 IC50 = 831 nM