Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US10028961, Compound 1
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 PubChem ID
CID: 117817069
Canonical SMILES
FC(F)(F)c1cccc(n1)-c1nc(NCC2CC2)nc(NCC2CC2)n1
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Compound Formula C17H19F3N6
Compound Structure
Protein Name
 Protein Info 
Isocitrate dehydrogenase [NADP], mitochondrial
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P48735
Gene Name
IDH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 13 nM
   TI
   LI
   LO
   TS
2
IC50 < 50 nM
   TI
   LI
   LO
   TS
CL000102 U-87MG ATCC
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 22 nM
   TI
   LI
   LO
   TS