Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(1H-imidazol-4-yl)ethan-1-amine
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 PubChem ID
CID: 774
SID: 16080673
Canonical SMILES
NCCc1cnc[nH]1
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Compound Formula C5H9N3
Compound Structure
Protein Name
 Protein Info 
Histamine H4 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q91ZY1
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000956 HEK293-SF-rH4R-His6-CRE-Luc
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 295.12 nM
   TI
   LI
   LO
   TS
CL000910 HEK293T-beta-arr2-rH4R
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 3715.35 nM
   TI
   LI
   LO
   TS
CL000074 SK-N-MC
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 63.1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 52480.75 nM
2 Kd = 134 nM
3 Ki = 136 nM