Brief Information of the Compound and Protein
Compound Name
(4R)-4-[(1S)-1-fluoroethyl]-3-[2-[[1-[1-[3-(trifluoromethyl)phenyl]imidazol-4-yl]cyclopropyl]amino]pyrimidin-4-yl]-1,3-oxazolidin-2-one
    Show/Hide
PubChem ID
CID: 155518356
Canonical SMILES
C[C@H](F)[C@H]1COC(=O)N1c1ccnc(NC2(CC2)c2cn(cn2)-c2cccc(c2)C(F)(F)F)n1
    Show/Hide
Compound Formula C22H20F4N6O2
Compound Structure
Protein Name
Isocitrate dehydrogenase [NADP] cytoplasmic
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
O75874
Gene Name
IDH1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080 Homo sapiens (Human)  1
1
IC50 = 10 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 32 nM