Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(4R)-3-[2-[[1-[1-(3-chloro-4-fluorophenyl)imidazol-4-yl]cyclobutyl]amino]pyrimidin-4-yl]-4-[(1S)-1-fluoroethyl]-1,3-oxazolidin-2-one
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 PubChem ID
CID: 155516944
Canonical SMILES
C[C@H](F)[C@H]1COC(=O)N1c1ccnc(NC2(CCC2)c2cn(cn2)-c2ccc(F)c(Cl)c2)n1
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Compound Formula C22H21ClF2N6O2
Compound Structure
Protein Name
 Protein Info 
Isocitrate dehydrogenase [NADP] cytoplasmic
Protein Classification
Enzyme
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Oxidoreductase
Uniprot ID
O75874
Gene Name
IDH1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 21 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 40 nM