Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(4R)-3-[2-[[1-[5-chloro-1-[3-(trifluoromethyl)phenyl]imidazol-4-yl]cyclopropyl]amino]pyrimidin-4-yl]-4-[(1S)-1-fluoroethyl]-1,3-oxazolidin-2-one
    Show/Hide
 PubChem ID
CID: 155556534
Canonical SMILES
C[C@H](F)[C@H]1COC(=O)N1c1ccnc(NC2(CC2)c2ncn(c2Cl)-c2cccc(c2)C(F)(F)F)n1
    Show/Hide
Compound Formula C22H19ClF4N6O2
Compound Structure
Protein Name
 Protein Info 
Isocitrate dehydrogenase [NADP] cytoplasmic
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
O75874
Gene Name
IDH1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 26 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 41 nM