Brief Information of the Compound and Protein
Compound Name
5-amino-2,4-dioxo-N-[(1R,4R)-4-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl]-1H-pyrimidine-6-carboxamide
    Show/Hide
PubChem ID
CID: 117926750
Canonical SMILES
Nc1c([nH]c(=O)[nH]c1=O)C(=O)N[C@@H]1CC[C@H](c2ccccc2)c2ccccc12
    Show/Hide
Compound Formula C21H20N4O3
Compound Structure
Protein Name
Endothelial lipase
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q9Y5X9
Gene Name
LIPG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7 Chlorocebus aethiops (Green monkey)  1
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 76000 nM