Brief Information of the Compound and Protein
Compound Name
5-hydroxy-3-(2-methylpropyl)-2,4-dioxo-N-(4-phenylcyclohexyl)-1H-pyrimidine-6-carboxamide
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Canonical SMILES
CC(C)Cn1c(=O)[nH]c(C(=O)N[C@H]2CC[C@H](CC2)c2ccccc2)c(O)c1=O
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Compound Formula C21H27N3O4
Compound Structure
Protein Name
Endothelial lipase
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q9Y5X9
Gene Name
LIPG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7 Chlorocebus aethiops (Green monkey)  1
1
IC50 = 59 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 48000 nM