Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-[[(1S)-1-(6-chloro-7-fluoro-2-oxo-1H-quinolin-3-yl)ethyl]amino]-1-methyl-6-oxopyridine-2-carbonitrile
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 PubChem ID
CID: 118955405
Canonical SMILES
C[C@H](Nc1ccc(C#N)n(C)c1=O)c1cc2cc(Cl)c(F)cc2[nH]c1=O
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Compound Formula C18H14ClFN4O2
Compound Structure
Protein Name
 Protein Info 
Isocitrate dehydrogenase [NADP] cytoplasmic
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
O75874
Gene Name
IDH1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000067 HCT 116
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 22 nM
   TI
   LI
   LO
   TS
2
IC50 = 104 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 25 nM
2 IC50 = 159 nM