Brief Information of the Compound and Protein
Compound Name
(2S)-2-[[4-[3-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-6-yl)propyl]thiophene-2-carbonyl]amino]pentanedioic acid
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PubChem ID
CID: 135567034
SID: 121265076
Canonical SMILES
Nc1nc2[nH]c(CCCc3csc(c3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cc2c(=O)[nH]1
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Compound Formula C19H21N5O6S
Compound Structure
Protein Name
Folate receptor beta
Protein Classification
Membrane receptor
Uniprot ID
P14207
Gene Name
FOLR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000344 D4 [Mouse hybridoma against human RICTOR] Mus musculus (Mouse)  2
1
IC50 = 0.34 nM
   TI
   LI
   LO
   TS
2
IC50 = 557 nM
   TI
   LI
   LO
   TS
CL000853 HeLa R1-11 Homo sapiens (Human)  1
1
IC50 = 7.57 nM
   TI
   LI
   LO
   TS