Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S)-2-(2-chlorophenyl)-N-(3,3-difluorocyclobutyl)-2-(3-fluoro-N-[2-[(2S)-1-pyrimidin-2-ylpyrrolidin-2-yl]acetyl]anilino)acetamide
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 PubChem ID
CID: 145980478
Canonical SMILES
Fc1cccc(c1)N([C@H](C(=O)NC1CC(F)(F)C1)c1ccccc1Cl)C(=O)C[C@@H]1CCCN1c1ncccn1
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Compound Formula C28H27ClF3N5O2
Compound Structure
Protein Name
 Protein Info 
Isocitrate dehydrogenase [NADP] cytoplasmic
Protein Classification
Enzyme
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Oxidoreductase
Uniprot ID
O75874
Gene Name
IDH1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 53 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 34 nM