Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S)-2-(2-chlorophenyl)-2-(N-[2-[(2S)-1-(4-cyanopyridin-2-yl)-5-oxopyrrolidin-2-yl]acetyl]-3-fluoro-5-sulfamoylanilino)-N-(3,3-difluorocyclobutyl)acetamide
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 PubChem ID
CID: 140267775
Canonical SMILES
NS(=O)(=O)c1cc(F)cc(c1)N([C@H](C(=O)NC1CC(F)(F)C1)c1ccccc1Cl)C(=O)C[C@@H]1CCC(=O)N1c1cc(ccn1)C#N
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Compound Formula C30H26ClF3N6O5S
Compound Structure
Protein Name
 Protein Info 
Isocitrate dehydrogenase [NADP] cytoplasmic
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
O75874
Gene Name
IDH1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 13 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 11 nM