Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S)-2-(2-chlorophenyl)-2-(N-[2-[(2S,4S)-1-(4-cyanopyrimidin-2-yl)-4-hydroxy-5-oxopyrrolidin-2-yl]acetyl]-3,5-difluoroanilino)-N-(3,3-difluorocyclobutyl)acetamide
    Show/Hide
 PubChem ID
CID: 145989869
Canonical SMILES
O[C@H]1C[C@@H](CC(=O)N([C@H](C(=O)NC2CC(F)(F)C2)c2ccccc2Cl)c2cc(F)cc(F)c2)N(C1=O)c1nccc(n1)C#N
    Show/Hide
Compound Formula C29H23ClF4N6O4
Compound Structure
Protein Name
 Protein Info 
Isocitrate dehydrogenase [NADP] cytoplasmic
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
O75874
Gene Name
IDH1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 297 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7 nM