Brief Information of the Compound and Protein
Compound Name
 Compound Info 
methyl (2S)-2-[2-(N-[(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl]-3-fluoroanilino)-2-oxoethyl]pyrrolidine-1-carboxylate
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 PubChem ID
CID: 145993302
Canonical SMILES
COC(=O)N1CCC[C@H]1CC(=O)N([C@H](C(=O)NC1CC(F)(F)C1)c1ccccc1Cl)c1cccc(F)c1
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Compound Formula C26H27ClF3N3O4
Compound Structure
Protein Name
 Protein Info 
Isocitrate dehydrogenase [NADP] cytoplasmic
Protein Classification
Enzyme
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Oxidoreductase
Uniprot ID
O75874
Gene Name
IDH1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 279 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 44 nM