Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(10S,14R)-N,14-dimethyl-6-(2-methylsulfonylpropan-2-yl)-N-(1H-pyrazol-5-yl)-8,12-dioxa-1,3,5-triazatricyclo[8.4.0.02,7]tetradeca-2,4,6-trien-4-amine
    Show/Hide
 PubChem ID
CID: 132179226
Canonical SMILES
C[C@@H]1COC[C@H]2COc3c(nc(nc3C(C)(C)S(C)(=O)=O)N(C)c3ccn[nH]3)N12
    Show/Hide
Compound Formula C18H26N6O4S
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase ATR
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Atypical protein kinase group
>
Atypical protein kinase PIKK family
Uniprot ID
Q13535
Gene Name
ATR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000007 HT-29
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 10 nM
   TI
   LI
   LO
   TS