Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[2-[7-methyl-3-[3-(trifluoromethyl)phenyl]isoquinolin-8-yl]ethynyl]-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-4-amine
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 PubChem ID
CID: 145983518
Canonical SMILES
CC(C)n1nc(C#Cc2c(C)ccc3cc(ncc23)-c2cccc(c2)C(F)(F)F)c2c(N)ncnc12
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Compound Formula C27H21F3N6
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000045 A-375
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 2300 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 44 nM