Brief Information of the Compound and Protein
Compound Name
[6-[[5-[[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]-1,2-thiazol-3-yl]methyl]pyridin-2-yl]methanol
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PubChem ID
CID: 145968638
Canonical SMILES
Cc1cn2c(cnc2c(Nc2cc(Cc3cccc(CO)n3)ns2)n1)-c1cn[nH]c1
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Compound Formula C20H18N8OS
Compound Structure
Protein Name
Aurora kinase B
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
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Other protein kinase group
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Other protein kinase AUR family
Uniprot ID
Q96GD4
Gene Name
AURKB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000067 HCT 116 Homo sapiens (Human)  1
1
EC50 = 559 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 < 13 nM