Brief Information of the Compound and Protein
Compound Name
3-(4-pyridin-2-ylpiperazin-1-yl)sulfonyl-6-[5-(trifluoromethyl)pyridin-3-yl]imidazo[1,2-b]pyridazine
    Show/Hide
PubChem ID
CID: 145966328
Canonical SMILES
FC(F)(F)c1cncc(c1)-c1ccc2ncc(n2n1)S(=O)(=O)N1CCN(CC1)c1ccccn1
    Show/Hide
Compound Formula C21H18F3N7O2S
Compound Structure
Protein Name
Tumor necrosis factor
Protein Classification
Secreted protein
Uniprot ID
P01375
Gene Name
TNF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1 Homo sapiens (Human)  1
1
IC50 = 11000 nM
   TI
   LI
   LO
   TS