Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-phenyl-1-[6-[5-(trifluoromethyl)pyridin-3-yl]imidazo[1,2-b]pyridazin-3-yl]sulfonylpiperidine-4-carbonitrile
    Show/Hide
 PubChem ID
CID: 145966692
Canonical SMILES
FC(F)(F)c1cncc(c1)-c1ccc2ncc(n2n1)S(=O)(=O)N1CCC(CC1)(C#N)c1ccccc1
    Show/Hide
Compound Formula C24H19F3N6O2S
Compound Structure
Protein Name
 Protein Info 
Tumor necrosis factor
Protein Classification
Secreted protein
Uniprot ID
P01375
Gene Name
TNF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 20000 nM
   TI
   LI
   LO
   TS