Brief Information of the Compound and Protein
Compound Name
1-[6-(4-methylsulfonylphenyl)imidazo[1,2-b]pyridazin-3-yl]sulfonyl-4-phenylpiperidine-4-carbonitrile
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PubChem ID
CID: 145977985
Canonical SMILES
CS(=O)(=O)c1ccc(cc1)-c1ccc2ncc(n2n1)S(=O)(=O)N1CCC(CC1)(C#N)c1ccccc1
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Compound Formula C25H23N5O4S2
Compound Structure
Protein Name
Tumor necrosis factor
Protein Classification
Secreted protein
Uniprot ID
P01375
Gene Name
TNF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1 Homo sapiens (Human)  1
1
IC50 = 8000 nM
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   LI
   LO
   TS