Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-[3-(4-pyridin-2-ylpiperazin-1-yl)sulfonylimidazo[1,2-b]pyridazin-6-yl]-3-(trifluoromethyl)pyridin-2-amine
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 PubChem ID
CID: 145964594
Canonical SMILES
Nc1ncc(cc1C(F)(F)F)-c1ccc2ncc(n2n1)S(=O)(=O)N1CCN(CC1)c1ccccn1
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Compound Formula C21H19F3N8O2S
Compound Structure
Protein Name
 Protein Info 
Tumor necrosis factor
Protein Classification
Secreted protein
Uniprot ID
P01375
Gene Name
TNF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 11000 nM
   TI
   LI
   LO
   TS