Brief Information of the Compound and Protein
Compound Name
1-(2-chloro-6-propan-2-yloxypyridin-4-yl)-3-[(1,3-dimethyl-4-propan-2-ylpyrazolo[3,4-b]pyridin-6-yl)amino]urea
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PubChem ID
CID: 145976329
Canonical SMILES
CC(C)Oc1cc(NC(=O)NNc2cc(C(C)C)c3c(C)nn(C)c3n2)cc(Cl)n1
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Compound Formula C20H26ClN7O2
Compound Structure
Protein Name
Sphingosine 1-phosphate receptor 3
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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EDG receptor
Uniprot ID
Q99500
Gene Name
S1PR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000064 Chem-1 Rattus norvegicus (Rat)  1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS