Brief Information of the Compound and Protein
Compound Name
N-[4-[[2-[[(2R)-1-hydroxypropan-2-yl]amino]-6-phenylquinazolin-4-yl]amino]cyclohexyl]-3-(propan-2-ylamino)cyclobutane-1-carboxamide
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Canonical SMILES
CC(C)N[C@H]1C[C@@H](C1)C(=O)N[C@H]1CC[C@@H](CC1)Nc1nc(N[C@H](C)CO)nc2ccc(cc12)-c1ccccc1
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Compound Formula C31H42N6O2
Compound Structure
Protein Name
Atrial natriuretic peptide receptor 1
Protein Classification
Enzyme
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Lyase
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Guanylate cyclase
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Receptor guanylate cyclase
Uniprot ID
P16066
Gene Name
NPR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 320 nM
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