Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[4-[[6-(3-fluorophenyl)-2-[[(2R)-1-hydroxypropan-2-yl]amino]quinazolin-4-yl]amino]cyclohexyl]-3-[(2R)-1-hydroxy-3-methylbutan-2-yl]urea
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Canonical SMILES
CC(C)[C@H](CO)NC(=O)N[C@H]1CC[C@H](CC1)Nc1nc(N[C@H](C)CO)nc2ccc(cc12)-c1cccc(F)c1
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Compound Formula C29H39FN6O3
Compound Structure
Protein Name
 Protein Info 
Atrial natriuretic peptide receptor 1
Protein Classification
Enzyme
>
Lyase
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Guanylate cyclase
>
Receptor guanylate cyclase
Uniprot ID
P16066
Gene Name
NPR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 71 nM
   TI
   LI
   LO
   TS