Brief Information of the Compound and Protein
Compound Name
1-[4-[[6-(3-fluorophenyl)-2-(propan-2-ylamino)quinazolin-4-yl]amino]cyclohexyl]-3-propan-2-ylurea
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Canonical SMILES
CC(C)NC(=O)N[C@H]1CC[C@H](CC1)Nc1nc(NC(C)C)nc2ccc(cc12)-c1cccc(F)c1
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Compound Formula C27H35FN6O
Compound Structure
Protein Name
Atrial natriuretic peptide receptor 1
Protein Classification
Enzyme
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Lyase
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Guanylate cyclase
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Receptor guanylate cyclase
Uniprot ID
P16066
Gene Name
NPR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 1500 nM
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