Brief Information of the Compound and Protein
Compound Name
1-[4-[[6-(3-fluorophenyl)-2-[[(2R)-1-methoxypropan-2-yl]amino]quinazolin-4-yl]amino]cyclohexyl]-3-propan-2-ylurea
    Show/Hide
Canonical SMILES
COC[C@@H](C)Nc1nc(N[C@@H]2CC[C@@H](CC2)NC(=O)NC(C)C)c2cc(ccc2n1)-c1cccc(F)c1
    Show/Hide
Compound Formula C28H37FN6O2
Compound Structure
Protein Name
Atrial natriuretic peptide receptor 1
Protein Classification
Enzyme
>
Lyase
>
Guanylate cyclase
>
Receptor guanylate cyclase
Uniprot ID
P16066
Gene Name
NPR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 200 nM
   TI
   LI
   LO
   TS