Brief Information of the Compound and Protein
Compound Name
N-[4-[[6-(3-fluorophenyl)-2-[[(2R)-1-hydroxypropan-2-yl]amino]quinazolin-4-yl]amino]cyclohexyl]-3-hydroxycyclobutane-1-carboxamide
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Canonical SMILES
C[C@H](CO)Nc1nc(N[C@H]2CC[C@@H](CC2)NC(=O)[C@H]2C[C@H](O)C2)c2cc(ccc2n1)-c1cccc(F)c1
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Compound Formula C28H34FN5O3
Compound Structure
Protein Name
Atrial natriuretic peptide receptor 1
Protein Classification
Enzyme
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Lyase
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Guanylate cyclase
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Receptor guanylate cyclase
Uniprot ID
P16066
Gene Name
NPR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 470 nM
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