Brief Information of the Compound and Protein
Compound Name
2-[1-(5-ethylpyrimidin-2-yl)piperidin-4-yl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]-1,3-thiazole
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PubChem ID
CID: 25025505
SID: 56376137
Canonical SMILES
CCc1cnc(nc1)N1CCC(CC1)c1nc(COc2ccc(cc2)-n2cnnn2)cs1
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Compound Formula C22H24N8OS
Compound Structure
Protein Name
Glucose-dependent insulinotropic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
Uniprot ID
Q8TDV5
Gene Name
GPR119
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 5000 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 87 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 3.9 nM