Brief Information of the Compound and Protein
Compound Name
1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol
    Show/Hide
PubChem ID
CID: 159603
SID: 12014952
Canonical SMILES
CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)O
    Show/Hide
Compound Formula C17H22N4O2
Compound Structure
Protein Name
Toll-like receptor 7
Protein Classification
Membrane receptor
>
Toll-like and Il-1 receptors
Uniprot ID
Q9NYK1
Gene Name
TLR7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000870 HEK-Blue Null1-v Homo sapiens (Human)  1
1
EC50 = 250 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  6
1
EC50 = 75 nM
   TI
   LI
   LO
   TS
2
EC50 = 260.1 nM
   TI
   LI
   LO
   TS
3
EC50 = 750 nM
   TI
   LI
   LO
   TS
4
EC50 = 1340 nM
   TI
   LI
   LO
   TS
5
EC50 = 1400 nM
   TI
   LI
   LO
   TS
6
EC50 = 1500 nM
   TI
   LI
   LO
   TS
CL000752 PBMC iPSC #1 Homo sapiens (Human)  1
1
Activity = 4.478514 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Activity = 39.759534 nM