Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(4R)-4-(fluoromethyl)-3-[2-[[(1S)-1-[4-methyl-5-[2-(trifluoromethyl)pyridin-4-yl]pyridin-2-yl]ethyl]amino]pyrimidin-4-yl]-1,3-oxazolidin-2-one
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 PubChem ID
CID: 145963523
Canonical SMILES
C[C@H](Nc1nccc(n1)N1[C@@H](CF)COC1=O)c1cc(C)c(cn1)-c1ccnc(c1)C(F)(F)F
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Compound Formula C22H20F4N6O2
Compound Structure
Protein Name
 Protein Info 
Isocitrate dehydrogenase [NADP] cytoplasmic
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
O75874
Gene Name
IDH1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000067 HCT 116
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 69 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 28 nM